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LEADseeker
Multimodality Imaging System can facilitate fluorescence-based bioassay
development and high-throughput drug screening. Now, in addition to
radiometric, luminescence, and fluorescence resonance energy transfer
(FRET) detection, LEADseeker can also perform fluorescence
polarization, time resolved fluorescence (TRF), and TR-FRET detection.
With the ability to detect light emitted by virtually any assay method
and the flexibility to accommodate any plate size, including 96, 384
and 1536 well formats, the LEADseeker Multimodality Imaging System is
the ultimate solution for high-throughput and ultra-high-throughput
screening (HTS) for drug discovery
Using state-of-the-art CCD technology, LEADseeker detects light emitted
from an entire microtiter plate at one time, regardless of the number
of wells. This ability saves an enormous amount of time compared to
conventional readers that scan plates one well at a time. Additionally,
the LEADseeker Multimodality Imaging System’s rapid plate transfer
system, sophisticated optics, and high-speed data processing
capabilities enable the instrument to process an entire microtiter
plate in less than 20 seconds —significantly faster than competing
detection systems.
- Fast: Capable of
screening
> 1.4 million compounds/day due to format-free
imaging, rapid plate cycling, fast data acquisition time, and data read-out.
- Ease of use: The instrument is almost
exclusively controlled from the flexible and intuitive AssayVision™
software interface, which also contains proven and accurate
quantitation algorithms for ease of data analysis and remote protocol
calling (via automation). Open architecture offers choice of automation
solution.
- Ref L003
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