Thermo Scientific Q Exactive PLUS Benchtop HRAM Orbitrap w/ IonMax HESI

Thermo Scientific™ Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer

Q Exactive plus Benchtop HRAM Orbitrap MS

IonMax Source with HESI ESI

Included items:

Sogevac Rough pump

Switching valve and Syringe pump

Cable, hoses and accessories

Software

Exactive / Xcalibur

Take Quanfirmation™ to the next level. The Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer introduced the revolutionary concept of Quanfirmation. The Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer takes Quanfirmation to the next level with increased performance and new options that enhance applications from confident DMPK qual/quan screening studies to characterization of intact monoclonal antibodies.

Description

Includes a Dionex Ultimate 3000 Analytical LC or NanoRS LC

Superior Quantitation

Advanced quadrupole technology (AQT) improves precursor selection and transmission for more-accurate quantitation of low-abundance analytes in complex matrices
Sophisticated data-independent acquisition (DIA) and parallel reaction monitoring (PRM) deliver reproducible quantitation with complete qualitative confidence
An advanced active beam guide (AABG) reduces noise and extends maintenance intervals

Enhanced Analysis of Intact Proteins

Optional intact protein mode provides superior trapping of large molecules for improved analysis of intact proteins and protein complexes
Optional enhanced resolution ensures maximum ID confidence in top-down proteomics and lipidomics

High-Confidence Results

HR/AM and full-scan capabilities capture all sample data, all of the time, enabling retrospective data analysis without need to re-run samples
Resolving power up to 140,000 FWHM eliminates isobaric interferences, increasing confidence in results when analyzing samples in complex matrices
Better than 1-ppm mass accuracy in full- and all-ion fragmentation (AIF) scan modes ensures confident compound identification
Fast scanning at 12 Hz and spectral multiplexing suited to UHPLC applications
Rapid polarity switching maximizes information obtained
AIF and multiple dissociation techniques — in-source CID and HCD — aid in compound identification
Mass range to 6000 m/z enhances detection of singly charged small molecules and biomolecules
More than four orders of magnitude intrascan dynamic range, along with femtogram-level sensitivity, allow detection of trace-level and high-abundance compounds in the same scan